Article Abstract

Is there a value for definition of human leukocyte antigen-associated peptidomes?

Authors: Robert Weissert

Abstract

In the article, Mass Spectrometry Profiling of HLA-Associated Peptidomes in Mono-allelic Cells Enables More Accurate Epitope Prediction by Abelin et al. (1) which was published in the February 2017 issue of Immunity the authors present a novel methodological approach to define peptidomes presented on major histocompatibility complex (MHC) class I alleles. The MHC of man is called human leukocyte antigen (HLA), of mice, H2, and of rats, RT1, to name a few examples of names of the MHC of different species that are relevant for biomedical research.

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