%0 Journal Article %T New exciting possibilities for the development of precision medicine therapies to restore the expression of the INK4/ARF locus %A Gamell, Cristina %A Haupt, Sue %A Haupt, Ygal %J Annals of Research Hospitals %D 2017 %B 2017 %9 %! New exciting possibilities for the development of precision medicine therapies to restore the expression of the INK4/ARF locus %K %X Loss of expression of the genes encoded in the INK4/ARF locus ( p14 ARF , p15 INK4B and p16 INK4A ) is a common event in human cancers (1). Recent publications shed light on the mechanisms involved in the INK4/ARF locus silencing, which opens an exciting window for the design of new therapeutic strategies for cancer patients. %U https://arh.amegroups.org/article/view/3798 %V 1 %P %@ 2523-0743