%0 Journal Article %T Brain N-acetylaspartate accumulation in Canavan disease is not neurotoxic per se: the implications of the first gene replacement therapy study to demonstrate successful post-symptomatic treatment in mice %A Elliott, Christina %A Al-Humadi, Hussam %A Gutierrez-Quintana, Rodrigo %A Zarros, Apostolos %J Annals of Research Hospitals %D 2018 %B 2018 %9 %! Brain N-acetylaspartate accumulation in Canavan disease is not neurotoxic per se: the implications of the first gene replacement therapy study to demonstrate successful post-symptomatic treatment in mice %K %X Canavan disease (CD) is identified as a fatal spongiform leukodystrophy caused by missense mutations in the Aspa gene (1,2). %U https://arh.amegroups.org/article/view/4314 %V 2 %P %@ 2523-0743